barry: Your go-to motif accountant
0.0-1
Full enumeration of sample space and fast count of sufficient statistics for binary arrays
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Counters for phylogenetic modeling. More...
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Phylo rules | |
Rules for phylogenetic modeling. | |
void | counter_overall_gains (PhyloCounters *counters, size_t duplication=Geese::etype_default) |
Overall functional gains. More... | |
void | counter_gains (PhyloCounters *counters, std::vector< size_t > nfun, size_t duplication=Geese::etype_default) |
Functional gains for a specific function (nfun ). More... | |
void | counter_gains_k_offspring (PhyloCounters *counters, std::vector< size_t > nfun, size_t k=1u, size_t duplication=Geese::etype_default) |
k genes gain function nfun More... | |
void | counter_genes_changing (PhyloCounters *counters, size_t duplication=Geese::etype_default) |
Keeps track of how many genes are changing (either 0, 1, or 2 if dealing with regular trees.) More... | |
void | counter_preserve_pseudogene (PhyloCounters *counters, size_t nfunA, size_t nfunB, size_t duplication=Geese::etype_default) |
Keeps track of how many pairs of genes preserve pseudostate. More... | |
void | counter_prop_genes_changing (PhyloCounters *counters, size_t duplication=Geese::etype_default) |
Keeps track of how many genes are changing (either 0, 1, or 2 if dealing with regular trees.) More... | |
void | counter_overall_loss (PhyloCounters *counters, size_t duplication=Geese::etype_default) |
Overall functional loss. More... | |
void | counter_maxfuns (PhyloCounters *counters, size_t lb, size_t ub, size_t duplication=Geese::etype_default) |
Cap the number of functions per gene. More... | |
void | counter_loss (PhyloCounters *counters, std::vector< size_t > nfun, size_t duplication=Geese::etype_default) |
Total count of losses for an specific function. More... | |
void | counter_overall_changes (PhyloCounters *counters, size_t duplication=Geese::etype_default) |
Total number of changes. Use this statistic to account for "preservation". More... | |
void | counter_subfun (PhyloCounters *counters, size_t nfunA, size_t nfunB, size_t duplication=Geese::etype_default) |
Total count of Sub-functionalization events. More... | |
void | counter_cogain (PhyloCounters *counters, size_t nfunA, size_t nfunB, size_t duplication=Geese::etype_default) |
Co-evolution (joint gain or loss) More... | |
void | counter_longest (PhyloCounters *counters, size_t duplication=Geese::etype_default) |
Longest branch mutates (either by gain or by loss) More... | |
void | counter_neofun (PhyloCounters *counters, size_t nfunA, size_t nfunB, size_t duplication=Geese::etype_default) |
Total number of neofunctionalization events. More... | |
void | counter_pairwise_neofun_singlefun (PhyloCounters *counters, size_t nfunA, size_t duplication=Geese::etype_default) |
Total number of neofunctionalization events sum_u sum_{w < u} [x(u,a)*(1 - x(w,a)) + (1 - x(u,a)) * x(w,a)] change stat: delta{x(u,a): 0->1} = 1 - 2 * x(w,a) More... | |
void | counter_neofun_a2b (PhyloCounters *counters, size_t nfunA, size_t nfunB, size_t duplication=Geese::etype_default) |
Total number of neofunctionalization events. More... | |
void | counter_co_opt (PhyloCounters *counters, size_t nfunA, size_t nfunB, size_t duplication=Geese::etype_default) |
Function co-opting. More... | |
void | counter_k_genes_changing (PhyloCounters *counters, size_t k, size_t duplication=Geese::etype_default) |
Indicator function. Equals to one if \(k\) genes changed and zero otherwise. More... | |
void | counter_less_than_p_prop_genes_changing (PhyloCounters *counters, double p, size_t duplication=Geese::etype_default) |
Indicator function. Equals to one if \(k\) genes changed and zero otherwise. More... | |
void | counter_gains_from_0 (PhyloCounters *counters, std::vector< size_t > nfun, size_t duplication=Geese::etype_default) |
Used when all the functions are in 0 (like the root node prob.) More... | |
void | counter_overall_gains_from_0 (PhyloCounters *counters, size_t duplication=Geese::etype_default) |
Used when all the functions are in 0 (like the root node prob.) More... | |
void | counter_pairwise_overall_change (PhyloCounters *counters, size_t duplication=Geese::etype_default) |
Used when all the functions are in 0 (like the root node prob.) More... | |
void | counter_pairwise_preserving (PhyloCounters *counters, size_t nfunA, size_t nfunB, size_t duplication=Geese::etype_default) |
Used when all the functions are in 0 (like the root node prob.) More... | |
void | counter_pairwise_first_gain (PhyloCounters *counters, size_t nfunA, size_t nfunB, size_t duplication=Geese::etype_default) |
Used when all the functions are in 0 (like the root node prob.) More... | |
Counters for phylogenetic modeling.
counters | A pointer to a PhyloCounters object (Counters <PhyloArray , PhyloCounterData >). |
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Function co-opting.
Function co-opting of functions A and B happens when, for example, function B is gained as a new featured leveraging what function A already does; without losing function A. The sufficient statistic is defined as follows:
\[ x_{pa}(1 - x_{pb})\sum_{i<j}\left[x_{ia}^p(1 - x_{ib}^p)x_{ja}^px_{jb}^p + x_{ja}^p(1 - x_{jb}^p)x_{ia}^px_{ib}^p\right] \]
This algorithm implements the change statistic.
Definition at line 1299 of file counters.hpp.
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Co-evolution (joint gain or loss)
Needs to specify pairs of functions (nfunA
, nfunB
).
Definition at line 794 of file counters.hpp.
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Functional gains for a specific function (nfun
).
Definition at line 99 of file counters.hpp.
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Used when all the functions are in 0 (like the root node prob.)
Needs to specify function a.
Definition at line 1633 of file counters.hpp.
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k genes gain function nfun
Definition at line 159 of file counters.hpp.
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Keeps track of how many genes are changing (either 0, 1, or 2 if dealing with regular trees.)
Definition at line 231 of file counters.hpp.
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Indicator function. Equals to one if \(k\) genes changed and zero otherwise.
Definition at line 1397 of file counters.hpp.
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Indicator function. Equals to one if \(k\) genes changed and zero otherwise.
< How many genes diverge the parent
Definition at line 1517 of file counters.hpp.
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Longest branch mutates (either by gain or by loss)
Definition at line 851 of file counters.hpp.
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Total count of losses for an specific function.
Definition at line 594 of file counters.hpp.
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Cap the number of functions per gene.
Definition at line 532 of file counters.hpp.
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Total number of neofunctionalization events.
Needs to specify pairs of function.
Definition at line 1021 of file counters.hpp.
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Total number of neofunctionalization events.
Needs to specify pairs of function.
Definition at line 1166 of file counters.hpp.
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Total number of changes. Use this statistic to account for "preservation".
Definition at line 646 of file counters.hpp.
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Overall functional gains.
Total number of gains (irrespective of the function).
Definition at line 61 of file counters.hpp.
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Used when all the functions are in 0 (like the root node prob.)
Needs to specify function a.
Definition at line 1699 of file counters.hpp.
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Overall functional loss.
Definition at line 484 of file counters.hpp.
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Used when all the functions are in 0 (like the root node prob.)
Needs to specify function a. sum x(a)^3(1-x(b))^3 + x(b)^3(1-x(a))^3 + x(a)^3 * x(b)^3 + (1 - x(a))^3 * (1-x(b))^3
Definition at line 1951 of file counters.hpp.
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Total number of neofunctionalization events sum_u sum_{w < u} [x(u,a)*(1 - x(w,a)) + (1 - x(u,a)) * x(w,a)] change stat: delta{x(u,a): 0->1} = 1 - 2 * x(w,a)
Definition at line 1102 of file counters.hpp.
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Used when all the functions are in 0 (like the root node prob.)
Needs to specify function a.
Definition at line 1747 of file counters.hpp.
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Used when all the functions are in 0 (like the root node prob.)
Needs to specify function a. sum x(a)^3(1-x(b))^3 + x(b)^3(1-x(a))^3 + x(a)^3 * x(b)^3 + (1 - x(a))^3 * (1-x(b))^3
Definition at line 1812 of file counters.hpp.
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Keeps track of how many pairs of genes preserve pseudostate.
Definition at line 300 of file counters.hpp.
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Keeps track of how many genes are changing (either 0, 1, or 2 if dealing with regular trees.)
Definition at line 382 of file counters.hpp.
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Total count of Sub-functionalization events.
It requires to specify data = {funA, funB}
Definition at line 705 of file counters.hpp.