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This is an example dataset to illustrate LUCID model. It is simulated by assuming there are 2 latent clusters in the data. We assume the exposures are associated with latent cluster which ultimately affects the PFAS concentration and liver injury in children. The latent clusters are also characterized by differential levels of metabolites.

Usage

sim_data

Format

A list with 5 matrices corresponding to exposures (G), omics data (Z), a continuous outcome, a binary outcome and 2 covariates (can be used either as CoX or CoY). Each matrice contains 2000 observations.

G

10 exposures

Z

10 metabolites

Y_normal

Outcome, PFAS concentration in children

Y_bninary

Bianry outcome, liver injury status

Covariates

2 continous covariates, can be treated as either CoX or CoY

X

Latent clusters