This is an example dataset to illustrate LUCID model. It is simulated by assuming there are 2 latent clusters in the data. We assume the exposures are associated with latent cluster which ultimately affects the PFAS concentration and liver injury in children. The latent clusters are also characterized by differential levels of metabolites.
Format
A list with 5 matrices corresponding to exposures (G), omics data (Z), a continuous outcome, a binary outcome and 2 covariates (can be used either as CoX or CoY). Each matrice contains 2000 observations.
- G
10 exposures
- Z
10 metabolites
- Y_normal
Outcome, PFAS concentration in children
- Y_bninary
Bianry outcome, liver injury status
- Covariates
2 continous covariates, can be treated as either CoX or CoY
- X
Latent clusters